These products are not for individual sale. All information provided herein is for informational purposes for B2B product introductions and is not meant as final information. All supplement fact panels must be reviewed prior to being put into commercial use.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
SOURCES
- National Library of Medicine (NIH): https://www.ncbi.nlm.nih.gov/books/NBK564301/
- Healthline: https://www.healthline.com/nutrition/alpha-lipoic-acid
- WebMD: https://www.webmd.com/vitamins/ai/ingredientmono-767/alpha-lipoic-acid
- Forbes: https://www.forbes.com/health/supplements/alpha-lipoic-acid-benefits/
- Lipoic acid. Science Direct. Accessed 10/9/2023.
- Li W, Yin L, Sun X. Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling. Cell Death Dis. 2020;11(599).
- Kim K, Kim J, Kim H, et al. Effect of α-lipoic acid on the development of human skin equivalents using a pumpless skin-on-a-chip model. International Journal of Molecular Sciences. 2021;22(4):2160.
- Mitochondria. National Human Genome Research Institute. Accessed 10/9/2023.
- Nguyen H, Gupta V. Alpha-lipoic acid. StatPearls. 2022.
- Nerve pain (neuralgia). HealthDirect. Accessed 10/9/2023.
- Zahra KF, Lefter R, Ali A, et al. The involvement of the oxidative stress status in cancer pathology: a double view on the role of the antioxidants. Oxidative Medicine and Cellular Longevity. 2021.
- Singh P, Barman B, Thakur MK. Oxidative stress-mediated memory impairment during aging and its therapeutic intervention by natural bioactive compounds. Frontiers in Aging Neuroscience. 2022;(14):944697.
- Salehi B, Berkay Yılmaz Y, Antika G, et al. J. Insights on the use of α-lipoic acid for therapeutic purposes. Biomolecules. 2019;9(8):356.
- AlMomen A, Blaurock-Busch E. Alpha-lipoic acid (ALA), fatty acid and promising chelating agent for neurological ailments. World Journal of Biological and Pharmaceutical Research. 2022;03(01), 009-014.
- Yuan Y, Zhao SW, Wen SQ, et al. Alpha-lipoic acid attenuates cadmium- and lead-induced neurotoxicity by inhibiting both endoplasmic-reticulum stress and activation of fas/fasl and mitochondrial apoptotic pathways in rat cerebral cortex. Neurotox Res. 2021;39(4):1103-1115.
- Cerebral cortex. Science Direct. Accessed 10/9/2023.
- Rajkumar V, Lee VR, Gupta V. Heavy metal toxicity. StatPearls. 2023.
- Inflammation. National Institute of Environmental Health Sciences. Accessed 10/9/2023.
- Nehring SM, Goyal A, Patel BC. C Reactive Protein. StatPearls; 2023.
- Capece U, Moffa S, Improta I, et al. Alpha-lipoic acid and glucose metabolism: a comprehensive update on biochemical and therapeutic features. Nutrients. 2022;15(1):18.
- Sharifi-Rad M, Anil Kumar NV, Zucca P, et al. Lifestyle, oxidative stress, and antioxidants: back and forth in the pathophysiology of chronic diseases. Frontiers in Physiology. 2020;11.
- What is heart failure?. National Heart, Lung and Blood Institute. Accessed 10/9/2023.
- Brown D, Perry J, Allen M. et al. Mitochondrial function as a therapeutic target in heart failure. Nat Rev Cardiol. 2017;14:238-250.
- López-Doménech G, Kittler JT. Mitochondrial regulation of local supply of energy in neurons. Current Opinion in Neurobiology. 2023;81.